1P49
Structure of Human Placental Estrone/DHEA Sulfatase
Summary for 1P49
Entry DOI | 10.2210/pdb1p49/pdb |
Descriptor | STERYL-SULFATASE, octyl beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | steroid biosynthesis, steroid sulfatase, estrone sulfate, dehydroepiandrosterone sulfate, human placental enzyme, endoplasmic reticulum membrane-bound, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Multi-pass membrane protein: P08842 |
Total number of polymer chains | 1 |
Total formula weight | 64214.03 |
Authors | Hernandez-Guzman, F.G.,Higashiyama, T.,Pangborn, W.,Osawa, Y.,Ghosh, D. (deposition date: 2003-04-21, release date: 2003-08-12, Last modification date: 2020-07-29) |
Primary citation | Hernandez-Guzman, F.G.,Higashiyama, T.,Pangborn, W.,Osawa, Y.,Ghosh, D. Structure of Human Estrone Sulfatase Suggests Functional Roles of Membrane Association J.Biol.Chem., 278:22989-22997, 2003 Cited by PubMed: 12657638DOI: 10.1074/jbc.M211497200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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