1N4M

Structure of Rb tumor suppressor bound to the transactivation domain of E2F-2

Summary for 1N4M

• Entry DOI: 10.2210/pdb1n4m/pdb
• Descriptor: Retinoblastoma Pocket, Transcription factor E2F2 (3 entities in total)
• Functional Keywords: protein-peptide complex, cell cycle
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q14209
• Total number of polymer chains: 5
• Total formula weight: 86735.13

Authors

Lee, C.,Chang, J.H.,Lee, H.S.,Cho, Y. (deposition date: 2002-10-31, release date: 2003-01-07, Last modification date: 2024-02-14)

• Primary citation: Lee, C.,Chang, J.H.,Lee, H.S.,Cho, Y.; Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor; GENES DEV., 16:3199-3212, 2002; PubMed: 12502741; DOI: 10.1101/gad.1046102

Experimental method

X-RAY DIFFRACTION (2.2 Å)