1JU5

Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy

1JU5 の概要

• エントリーDOI: 10.2210/pdb1ju5/pdb
• 関連するPDBエントリー: 1AWO 1AYA 1BBZ 1SPS 2ABL 2PLD
• 分子名称: Crk, Abl (3 entities in total)
• 機能のキーワード: crk, sh2, abl, sh3, adaptor protein, phosphopeptide, protein binding-transferase complex, protein binding/transferase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm (By similarity): P46108 Q64010; Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 20375.51

構造登録者

Donaldson, L.W.,Pawson, T.,Kay, L.E.,Forman-Kay, J.D. (登録日: 2001-08-23, 公開日: 2002-11-06, 最終更新日: 2021-11-10)

• 主引用文献: Donaldson, L.W.,Gish, G.,Pawson, T.,Kay, L.E.,Forman-Kay, J.D.; Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide; Proc.Natl.Acad.Sci.USA, 99:14053-14058, 2002; PubMed: 12384576; DOI: 10.1073/pnas.212518799

実験手法

SOLUTION NMR