1JOC
EEA1 homodimer of C-terminal FYVE domain bound to inositol 1,3-diphosphate
Summary for 1JOC
| Entry DOI | 10.2210/pdb1joc/pdb |
| Descriptor | Early Endosomal Autoantigen 1, ZINC ION, PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER, ... (4 entities in total) |
| Functional Keywords | fyve domain, inositol 3-phosphate binding, membrane protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q15075 |
| Total number of polymer chains | 2 |
| Total formula weight | 29220.02 |
| Authors | Dumas, J.J.,Merithew, E.,Rajamani, D.,Hayes, S.,Lawe, D.,Corvera, S.,Lambright, D.G. (deposition date: 2001-07-27, release date: 2001-12-28, Last modification date: 2024-02-07) |
| Primary citation | Dumas, J.J.,Merithew, E.,Sudharshan, E.,Rajamani, D.,Hayes, S.,Lawe, D.,Corvera, S.,Lambright, D.G. Multivalent endosome targeting by homodimeric EEA1. Mol.Cell, 8:947-958, 2001 Cited by PubMed: 11741531DOI: 10.1016/S1097-2765(01)00385-9 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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