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1JHT

Crystal structure of HLA-A2*0201 in complex with a nonameric altered peptide ligand (ALGIGILTV) from the MART-1/Melan-A.

Summary for 1JHT
Entry DOI10.2210/pdb1jht/pdb
Related1JF1
DescriptorHLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, beta-2-microglobulin, nonameric peptide ligand from the MART-1/Melan-A, ... (4 entities in total)
Functional Keywordshuman, tumor immunity, melanoma antigen, mhc, vaccination, melanoma, class i, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted: P61769
Total number of polymer chains3
Total formula weight44589.62
Authors
Sliz, P.,Michielin, O.,Karplus, M.,Romero, P.,Wiley, D. (deposition date: 2001-06-28, release date: 2001-09-14, Last modification date: 2023-08-16)
Primary citationSliz, P.,Michielin, O.,Cerottini, J.C.,Luescher, I.,Romero, P.,Karplus, M.,Wiley, D.C.
Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes.
J.Immunol., 167:3276-3284, 2001
Cited by
PubMed: 11544315
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.15 Å)
Structure validation

217705

數據於2024-03-27公開中

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