1JAP

COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM)

Summary for 1JAP

Entry DOI	10.2210/pdb1jap/pdb
Related PRD ID	PRD_000404
Descriptor	MATRIX METALLO PROTEINASE-8 (MET80 FORM), PRO-LEU-GLY-HYDROXYLAMINE, CALCIUM ION, ... (5 entities in total)
Functional Keywords	metalloprotease, zinc-endopeptidase, metzincins, complex (metalloprotease-inhibitor) complex, complex (metalloprotease/inhibitor)
Biological source	Homo sapiens (human)
Cellular location	Cytoplasmic granule: P22894
Total number of polymer chains	2
Total formula weight	18623.07
Authors	Bode, W.,Reinemer, P.,Huber, R.,Kleine, T.,Schnierer, S.,Tschesche, H. (deposition date: 1996-03-11, release date: 1996-07-11, Last modification date: 2013-02-27)
Primary citation	Bode, W.,Reinemer, P.,Huber, R.,Kleine, T.,Schnierer, S.,Tschesche, H. The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity. EMBO J., 13:1263-1269, 1994 Cited by PubMed: 8137810 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation