1I1F

Crystal structure of human class i mhc (hla-a2.1) complexed with beta 2-microglobulin and hiv-rt variant peptide i1y

Summary for 1I1F

Entry DOI	10.2210/pdb1i1f/pdb
Descriptor	PROTEIN (CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-A0201 ALPHA CHAIN), PROTEIN (BETA 2-MICROGLOBULIN), PROTEIN (HIV-RT VARIANT PEPTIDE I1F (FLKEPVHGV)) (3 entities in total)
Functional Keywords	human class i mhc, hiv, immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769
Total number of polymer chains	6
Total formula weight	89521.55
Authors	Kirksey, T.J.,Pogue-Caley, R.R.,Frelinger, J.A.,Collins, E.J. (deposition date: 1999-04-16, release date: 2000-01-12, Last modification date: 2023-08-09)
Primary citation	Kirksey, T.J.,Pogue-Caley, R.R.,Frelinger, J.A.,Collins, E.J. The structural basis for the increased immunogenicity of two HIV-reverse transcriptase peptide variant/class I major histocompatibility complexes. J.Biol.Chem., 274:37259-37264, 1999 Cited by PubMed: 10601290 DOI: 10.1074/jbc.274.52.37259 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation