1HRN

HIGH RESOLUTION CRYSTAL STRUCTURES OF RECOMBINANT HUMAN RENIN IN COMPLEX WITH POLYHYDROXYMONOAMIDE INHIBITORS

1HRN の概要

• エントリーDOI: 10.2210/pdb1hrn/pdb
• 分子名称: RENIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, (2R,4S,5S)-N-[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-(cyclopropylmethyl)-4,5-dihydroxy-6-phenylhexanamide, ... (4 entities in total)
• 機能のキーワード: aspartic proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75329.03

構造登録者

Tong, L.,Anderson, P.C. (登録日: 1995-03-31, 公開日: 1995-06-03, 最終更新日: 2020-07-29)

• 主引用文献: Tong, L.,Pav, S.,Lamarre, D.,Pilote, L.,LaPlante, S.,Anderson, P.C.,Jung, G.; High resolution crystal structures of recombinant human renin in complex with polyhydroxymonoamide inhibitors.; J.Mol.Biol., 250:211-222, 1995; PubMed: 7608971; DOI: 10.1006/jmbi.1995.0372

実験手法

X-RAY DIFFRACTION (1.8 Å)