1H3H

Structural Basis for Specific Recognition of an RxxK-containing SLP-76 peptide by the Gads C-terminal SH3 domain

Summary for 1H3H

• Entry DOI: 10.2210/pdb1h3h/pdb
• Descriptor: GRB2-RELATED ADAPTOR PROTEIN 2, LYMPHOCYTE CYTOSOLIC PROTEIN 2 (2 entities in total)
• Functional Keywords: protein-binding, complex (sh3-peptide), t-cell signaling, sh3 domain, sh2 domain, protein binding
• Biological source: MUS MUSCULUS (HOUSE MOUSE); More
• Cellular location: Nucleus (By similarity): O89100
• Total number of polymer chains: 2
• Total formula weight: 8093.09

Authors

Liu, Q.,Berry, D.,Nash, P.,Pawson, T.,McGlade, C.J.,Li, S.S. (deposition date: 2002-09-03, release date: 2003-03-06, Last modification date: 2013-07-24)

• Primary citation: Liu, Q.,Berry, D.,Nash, P.,Pawson, T.,Mcglade, C.J.,Li, S.S.; Structural Basis for Specific Binding of the Gads SH3 Domain to an Rxxk Motif-Containing Slp-76 Peptide: A Novel Mode of Peptide Recognition; Mol.Cell, 11:471-, 2003; PubMed: 12620234; DOI: 10.1016/S1097-2765(03)00046-7

Experimental method

SOLUTION NMR