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1H25

CDK2/Cyclin A in complex with an 11-residue recruitment peptide from retinoblastoma-associated protein

Summary for 1H25
Entry DOI10.2210/pdb1h25/pdb
Related1AD6 1AQ1 1B38 1B39 1BUH 1CKP 1DI8 1DM2 1E1V 1E1X 1E9H 1F5Q 1FIN 1FQ1 1FVT 1FVV 1G5S 1GH6 1GIH 1GII 1GIJ 1GUX 1GY3 1GZ8 1QMZ
DescriptorCELL DIVISION PROTEIN KINASE 2, CYCLIN A2, RETINOBLASTOMA-ASSOCIATED PROTEIN, ... (4 entities in total)
Functional Keywordstransferase, cell cycle, protein kinase, cyclin, cdk2, recruitment, peptide specificity
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationNucleus: P20248 P06400
Total number of polymer chains5
Total formula weight129785.34
Authors
Tews, I.,Cheng, K.Y.,Lowe, E.D.,Noble, M.E.M.,Brown, N.R.,Gul, S.,Gamblin, S.,Johnson, L.N. (deposition date: 2002-07-31, release date: 2003-02-01, Last modification date: 2023-12-13)
Primary citationLowe, E.D.,Tews, I.,Cheng, K.Y.,Brown, N.R.,Gul, S.,Noble, M.E.M.,Gamblin, S.,Johnson, L.N.
Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41:15625-, 2002
Cited by
PubMed: 12501191
DOI: 10.1021/BI0268910
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

數據於2024-03-27公開中

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