1H1W
High resolution crystal structure of the human PDK1 catalytic domain
Summary for 1H1W
Entry DOI | 10.2210/pdb1h1w/pdb |
Descriptor | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, SULFATE ION, ... (5 entities in total) |
Functional Keywords | transferase, phosphoinositide dependent protein kinase, pka, agc kinase activation, pif-pocket, pi3-kinase signalling, serine/threonine-protein kinase, atp-binding |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: O15530 |
Total number of polymer chains | 1 |
Total formula weight | 35176.72 |
Authors | Biondi, R.M.,Komander, D.,Thomas, C.C.,Lizcano, J.M.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F. (deposition date: 2002-07-23, release date: 2003-07-17, Last modification date: 2023-12-13) |
Primary citation | Biondi, R.M.,Komander, D.,Thomas, C.C.,Lizcano, J.M.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F. High Resolution Crystal Structure of the Human Pdk1 Catalytic Domain Defines the Regulatory Phosphopeptide Docking Site Embo J., 21:4219-, 2003 Cited by PubMed: 12169624DOI: 10.1093/EMBOJ/CDF437 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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