1H1W

High resolution crystal structure of the human PDK1 catalytic domain

1H1W の概要

• エントリーDOI: 10.2210/pdb1h1w/pdb
• 分子名称: 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: transferase, phosphoinositide dependent protein kinase, pka, agc kinase activation, pif-pocket, pi3-kinase signalling, serine/threonine-protein kinase, atp-binding
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Cytoplasm: O15530
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35176.72

構造登録者

Biondi, R.M.,Komander, D.,Thomas, C.C.,Lizcano, J.M.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F. (登録日: 2002-07-23, 公開日: 2003-07-17, 最終更新日: 2023-12-13)

• 主引用文献: Biondi, R.M.,Komander, D.,Thomas, C.C.,Lizcano, J.M.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F.; High Resolution Crystal Structure of the Human Pdk1 Catalytic Domain Defines the Regulatory Phosphopeptide Docking Site; Embo J., 21:4219-, 2003; PubMed: 12169624; DOI: 10.1093/EMBOJ/CDF437

実験手法

X-RAY DIFFRACTION (2 Å)