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1H1Q

Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6094

Summary for 1H1Q
Entry DOI10.2210/pdb1h1q/pdb
Related1AQ1 1B38 1B39 1BUH 1CKP 1DI8 1DM2 1E1V 1E1X 1E9H 1F5Q 1FIN 1FQ1 1FVT 1FVV 1G5S 1GIH 1GII 1GIJ 1GY3 1GZ8 1H00 1H01 1H06 1H07 1H08 1H0U 1H0V 1H0W 1H1P 1H1R 1H1S 1HCK 1HCL 1JST 1JSU 1JSV 1JVP 1KE5 1KE6 1KE7 1KE8 1KE9 1QMZ
DescriptorCELL DIVISION PROTEIN KINASE 2, CYCLIN A2, 2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE, ... (4 entities in total)
Functional Keywordskinase, transferase, serine/threonine-protein kinase, atp-binding, cell cycle, cell division, mitosis, phosphorylation
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationNucleus: P20248
Total number of polymer chains4
Total formula weight128831.23
Authors
Davies, T.G.,Noble, M.E.M.,Endicott, J.A.,Johnson, L.N. (deposition date: 2002-07-21, release date: 2002-09-19, Last modification date: 2011-07-13)
Primary citationDavies, T.G.,Bentley, J.,Arris, C.E.,Boyle, F.T.,Curtin, N.J.,Endicott, J.A.,Gibson, A.E.,Golding, B.T.,Griffin, R.J.,Hardcastle, I.R.,Jewsbury, P.,Johnson, L.N.,Mesguiche, V.,Newell, D.R.,Noble, M.E.M.,Tucker, J.A.,Wang, L.,Whitfield, H.J.
Structure-Based Design of a Potent Purine-Based Cyclin-Dependent Kinase Inhibitor
Nat.Struct.Biol., 9:745-, 2002
Cited by
PubMed: 12244298
DOI: 10.1038/NSB842
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

数据于2024-03-27公开中

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