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1E9H

Thr 160 phosphorylated CDK2 - Human cyclin A3 complex with the inhibitor indirubin-5-sulphonate bound

Summary for 1E9H
Entry DOI10.2210/pdb1e9h/pdb
Related1AQ1 1B38 1B39 1CKP 1DM2 1E1V 1E1X 1FIN 1HCK 1HCL 1JST 1JSU 1QMZ
DescriptorCELL DIVISION PROTEIN KINASE 2, CYCLIN A3, 2',3-DIOXO-1,1',2',3-TETRAHYDRO-2,3'-BIINDOLE-5'-SULFONIC ACID, ... (4 entities in total)
Functional Keywordscell cycle, complex (protein kinase-cyclin), kinases, inhibitor, cyclin, complex, phosphorylation
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationNucleus: P20248
Total number of polymer chains4
Total formula weight128360.47
Authors
Davies, T.G.,Tunnah, P.,Noble, M.E.M.,Endicott, J.A. (deposition date: 2000-10-16, release date: 2001-10-11, Last modification date: 2011-07-13)
Primary citationDavies, T.G.,Tunnah, P.,Meijer, L.,Marko, D.,Eisenbrand, G.,Endicott, J.A.,Noble, M.E.
Inhibitor Binding to Active and Inactive Cdk2: The Crystal Structure of Cdk2-Cyclin A/Indirubin-5-Sulphonate
Structure, 9:389-, 2001
Cited by
PubMed: 11377199
DOI: 10.1016/S0969-2126(01)00598-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

건을2024-03-27부터공개중

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