1DVA

Crystal Structure of the Complex Between the Peptide Exosite Inhibitor E-76 and Coagulation Factor VIIA

Summary for 1DVA

• Entry DOI: 10.2210/pdb1dva/pdb
• Related: 1CVW 1DAN 1FAK 1QFK
• Related PRD ID: PRD_000369 PRD_900004
• Descriptor: DES-GLA FACTOR VIIA (HEAVY CHAIN), beta-L-fucopyranose, DES-GLA FACTOR VIIA (LIGHT CHAIN), ... (11 entities in total)
• Functional Keywords: protein-peptide complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 85049.09

Authors

Eigenbrot, C.,Ultsch, M.H. (deposition date: 2000-01-20, release date: 2000-05-12, Last modification date: 2020-07-29)

• Primary citation: Dennis, M.S.,Eigenbrot, C.,Skelton, N.J.,Ultsch, M.H.,Santell, L.,Dwyer, M.A.,O'Connell, M.P.,Lazarus, R.A.; Peptide exosite inhibitors of factor VIIa as anticoagulants.; Nature, 404:465-470, 2000; PubMed: 10761907; DOI: 10.1038/35006574

Experimental method

X-RAY DIFFRACTION (3 Å)