1D1V

BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH S-ETHYL-N-PHENYL-ISOTHIOUREA (H4B BOUND)

Summary for 1D1V

Entry DOI	10.2210/pdb1d1v/pdb
Related	1D0C 1D0O 1D1V 1D1W 1D1X 1D1Y 1NSE
Descriptor	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME, ACETATE ION, ZINC ION, ... (9 entities in total)
Functional Keywords	alpha-beta fold, oxidoreductase
Biological source	Bos taurus (cattle)
Cellular location	Cell membrane: P29473
Total number of polymer chains	2
Total formula weight	102257.99
Authors	Raman, C.S.,Li, H.,Martasek, P.,Southan, G.J.,Masters, B.S.S.,Poulos, T.L. (deposition date: 1999-09-21, release date: 2001-07-25, Last modification date: 2024-02-07)
Primary citation	Raman, C.S.,Li, H.,Martasek, P.,Babu, B.R.,Griffith, O.W.,Masters, B.S.,Poulos, T.L. Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase. J.Biol.Chem., 276:26486-26491, 2001 Cited by PubMed: 11331290 DOI: 10.1074/jbc.M102255200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation