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1CKP

HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR PURVALANOL B

Summary for 1CKP
Entry DOI10.2210/pdb1ckp/pdb
DescriptorPROTEIN (CYCLIN-DEPENDENT PROTEIN KINASE 2), PURVALANOL B, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsprotein kinase, cell cycle, phosphorylation, cell division, mitosis, inhibition, hormone-growth factor complex, hormone/growth factor
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight34471.46
Authors
Gray, N.S.,Thunnissen, A.M.W.H.,Schultz, P.G.,Kim, S.H. (deposition date: 1998-07-14, release date: 1999-01-13, Last modification date: 2023-08-09)
Primary citationGray, N.S.,Wodicka, L.,Thunnissen, A.M.,Norman, T.C.,Kwon, S.,Espinoza, F.H.,Morgan, D.O.,Barnes, G.,LeClerc, S.,Meijer, L.,Kim, S.H.,Lockhart, D.J.,Schultz, P.G.
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.
Science, 281:533-538, 1998
Cited by
PubMed: 9677190
DOI: 10.1126/science.281.5376.533
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

217705

数据于2024-03-27公开中

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