1BBZ

CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH A DESIGNED HIGH-AFFINITY PEPTIDE LIGAND: IMPLICATIONS FOR SH3-LIGAND INTERACTIONS

Summary for 1BBZ

• Entry DOI: 10.2210/pdb1bbz/pdb
• Descriptor: ABL TYROSINE KINASE, PEPTIDE P41, SULFATE ION, ... (4 entities in total)
• Functional Keywords: complex (transferase-peptide), signal transduction, sh3 domain, complex (transferase-peptide) complex, complex (transferase/peptide)
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519
• Total number of polymer chains: 8
• Total formula weight: 30217.17

Authors

Pisabarro, M.T.,Serrano, L.,Wilmanns, M. (deposition date: 1998-04-28, release date: 1998-11-25, Last modification date: 2023-08-02)

• Primary citation: Pisabarro, M.T.,Serrano, L.,Wilmanns, M.; Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions.; J.Mol.Biol., 281:513-521, 1998; PubMed: 9698566; DOI: 10.1006/jmbi.1998.1932

Experimental method

X-RAY DIFFRACTION (1.65 Å)