185D

SEQUENCE SPECIFICITY OF QUINOXALINE ANTIBIOTICS. 1. SOLUTION STRUCTURE OF A 1:1 COMPLEX BETWEEN TRIOSTIN A AND [D(GACGTC)]2 AND COMPARISON WITH THE SOLUTION STRUCTURE OF THE [N-MECYS3, N-MECYS7]TANDEM-[D(GATATC)]2 COMPLEX

Summary for 185D

• Entry DOI: 10.2210/pdb185d/pdb
• Related: 193D 1PFE 1VS2 1XVK 1XVN 1XVR 2ADW 2DA8 3GO3
• Related PRD ID: PRD_000488
• Descriptor: TRIOSTIN A, DNA (5'-D(*GP*AP*CP*GP*TP*C)-3'), 2-CARBOXYQUINOXALINE (3 entities in total)
• Functional Keywords: bisintercalator, depsipeptide, quinoxaline, antibiotic, antitumor, dna-antibiotic complex, dna/antibiotic
• Biological source: STREPTOMYCINEAE
• Total number of polymer chains: 3
• Total formula weight: 4761.73

Authors

Addess, K.J.,Feigon, J. (deposition date: 1994-08-10, release date: 1995-02-07, Last modification date: 2017-11-01)

• Primary citation: Addess, K.J.,Feigon, J.; Sequence Specificity of Quinoxaline Antibiotics. 1. Solution Structure of a 1:1 Complex between Triostin a and [D(Gacgtc)]2 and Comparison with the Solution Structure of the [N-Mecys3,N-Mecys7]Tandem-[D(Gatatc)]2 Complex.; Biochemistry, 33:12386-, 1994; PubMed: 7918461; DOI: 10.1021/BI00207A005

Experimental method

SOLUTION NMR