9KDW

Cryo-EM structure of 80S ribosome

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (L5)	Mus musculus 28S ribosomal RNA	polymer	4731	1530907.4	1		Mus musculus (house mouse)
2	B (L7)	Mus musculus 5S ribosomal RNA	polymer	120	38691.9	1	GenBank (2589141237)	Mus musculus (house mouse)
3	C (L8)	Mus musculus 5.8S ribosomal RNA	polymer	158	50795.0	1		Mus musculus (house mouse)
4	D (LA)	Large ribosomal subunit protein uL2	polymer	257	28088.9	1	UniProt (P62918) Pfam (PF00181) Pfam (PF03947)	Mus musculus (house mouse)	60S ribosomal protein L8
5	E (LB)	Large ribosomal subunit protein uL3	polymer	403	46212.1	1	UniProt (P27659) Pfam (PF00297)	Mus musculus (house mouse)	60S ribosomal protein L3,J1 protein
6	F (LC)	Large ribosomal subunit protein uL4	polymer	419	47259.9	1	UniProt (Q9D8E6) Pfam (PF00573) Pfam (PF14374)	Mus musculus (house mouse)	60S ribosomal protein L4
7	G (LD)	Large ribosomal subunit protein uL18	polymer	297	34464.8	1	UniProt (P47962) Pfam (PF17144) Pfam (PF14204)	Mus musculus (house mouse)	60S ribosomal protein L5
8	H (LE)	Large ribosomal subunit protein eL6	polymer	296	33593.9	1	UniProt (P47911) Pfam (PF03868) Pfam (PF01159)	Mus musculus (house mouse)	60S ribosomal protein L6,TAX-responsive enhancer element-binding protein 107,TAXREB107
9	I (LF)	Large ribosomal subunit protein uL30	polymer	270	31492.9	1	UniProt (P14148) Pfam (PF08079) Pfam (PF00327)	Mus musculus (house mouse)	60S ribosomal protein L7
10	J (LG)	Large ribosomal subunit protein eL8	polymer	266	30042.7	1	UniProt (P12970) Pfam (PF01248)	Mus musculus (house mouse)	60S ribosomal protein L7a,Surfeit locus protein 3
11	K (LH)	Large ribosomal subunit protein uL6	polymer	192	21917.5	1	UniProt (P51410) Pfam (PF00347)	Mus musculus (house mouse)	60S ribosomal protein L9
12	L (LI)	Large ribosomal subunit protein uL16-like	polymer	214	24612.0	1	UniProt (P86048) Pfam (PF00252)	Mus musculus (house mouse)	60S ribosomal protein L10-like
13	M (LJ)	Large ribosomal subunit protein uL5	polymer	178	20288.5	1	UniProt (Q9CXW4) Pfam (PF00281) Pfam (PF00673)	Mus musculus (house mouse)	60S ribosomal protein L11
14	N (LL)	Large ribosomal subunit protein eL13	polymer	211	24364.7	1	UniProt (P47963) Pfam (PF01294)	Mus musculus (house mouse)	60S ribosomal protein L13,A52
15	O (LM)	Large ribosomal subunit protein eL14	polymer	217	23620.3	1	UniProt (Q9CR57) Pfam (PF01929)	Mus musculus (house mouse)	60S ribosomal protein L14
16	P (LN)	Large ribosomal subunit protein eL15	polymer	204	24207.3	1	UniProt (Q9CZM2) Pfam (PF00827)	Mus musculus (house mouse)	60S ribosomal protein L15
17	Q (LO)	Large ribosomal subunit protein uL13	polymer	203	23519.4	1	UniProt (P19253) Pfam (PF00572)	Mus musculus (house mouse)	60S ribosomal protein L13a,Transplantation antigen P198,Tum-P198 antigen
18	R (LP)	Large ribosomal subunit protein uL22	polymer	184	21444.2	1	UniProt (Q9CPR4) Pfam (PF00237)	Mus musculus (house mouse)	60S ribosomal protein L17
19	S (LQ)	Large ribosomal subunit protein eL18	polymer	188	21698.7	1	UniProt (P35980) Pfam (PF17135)	Mus musculus (house mouse)	60S ribosomal protein L18
20	T (LR)	Large ribosomal subunit protein eL19	polymer	196	23535.3	1	UniProt (P84099) Pfam (PF01280) Pfam (PF25476)	Mus musculus (house mouse)	60S ribosomal protein L19
21	U (LS)	Large ribosomal subunit protein eL20	polymer	176	20778.5	1	UniProt (P62717) Pfam (PF01775)	Mus musculus (house mouse)	60S ribosomal protein L18a
22	V (LT)	Large ribosomal subunit protein eL21	polymer	160	18624.0	1	UniProt (O09167) Pfam (PF01157)	Mus musculus (house mouse)	60S ribosomal protein L21
23	W (LU)	Large ribosomal subunit protein eL22	polymer	128	14785.0	1	UniProt (P67984) Pfam (PF01776)	Mus musculus (house mouse)	60S ribosomal protein L22,Heparin-binding protein HBp15
24	X (LV)	Large ribosomal subunit protein uL14	polymer	140	14892.5	1	UniProt (P62830) Pfam (PF00238)	Mus musculus (house mouse)	60S ribosomal protein L23
25	Y (LW)	Large ribosomal subunit protein eL24	polymer	157	17825.1	1	UniProt (Q8BP67) Pfam (PF01246)	Mus musculus (house mouse)	60S ribosomal protein L24
26	Z (LX)	Large ribosomal subunit protein uL23	polymer	156	17740.2	1	UniProt (P62751) Pfam (PF03939) Pfam (PF00276)	Mus musculus (house mouse)	60S ribosomal protein L23a
27	AA (LY)	Large ribosomal subunit protein uL24	polymer	145	17303.4	1	UniProt (P61255) Pfam (PF16906) Pfam (PF00467)	Mus musculus (house mouse)	60S ribosomal protein L26,Silica-induced gene 20 protein,SIG-20
28	BA (LZ)	Large ribosomal subunit protein eL27	polymer	136	15835.8	1	UniProt (P61358) Pfam (PF00467) Pfam (PF01777)	Mus musculus (house mouse)	60S ribosomal protein L27
29	CA (La)	Large ribosomal subunit protein uL15	polymer	148	16648.6	1	UniProt (P14115) Pfam (PF00828)	Mus musculus (house mouse)	60S ribosomal protein L27a,L29
30	DA (Lb)	Large ribosomal subunit protein eL29	polymer	160	17635.2	1	UniProt (P47915) Pfam (PF01779)	Mus musculus (house mouse)	60S ribosomal protein L29
31	EA (Lc)	Large ribosomal subunit protein eL30	polymer	115	12805.1	1	UniProt (P62889) Pfam (PF01248)	Mus musculus (house mouse)	60S ribosomal protein L30
32	FA (Ld)	Large ribosomal subunit protein eL31	polymer	125	14494.9	1	UniProt (P62900) Pfam (PF01198)	Mus musculus (house mouse)	60S ribosomal protein L31
33	GA (Le)	Large ribosomal subunit protein eL32	polymer	135	15898.9	1	UniProt (P62911) Pfam (PF01655)	Mus musculus (house mouse)	60S ribosomal protein L32
34	HA (Lf)	Large ribosomal subunit protein eL33	polymer	110	12580.8	1	UniProt (O55142) Pfam (PF01247)	Mus musculus (house mouse)	60S ribosomal protein L35a
35	IA (Lg)	Large ribosomal subunit protein eL34	polymer	117	13325.0	1	UniProt (Q9D1R9) Pfam (PF01199)	Mus musculus (house mouse)	60S ribosomal protein L34
36	JA (Lh)	Large ribosomal subunit protein uL29	polymer	123	14595.7	1	UniProt (Q6ZWV7) Pfam (PF00831)	Mus musculus (house mouse)	60S ribosomal protein L35
37	KA (Li)	Large ribosomal subunit protein eL36	polymer	105	12290.9	1	UniProt (P47964) Pfam (PF01158)	Mus musculus (house mouse)	60S ribosomal protein L36
38	LA (Lj)	Large ribosomal subunit protein eL37	polymer	97	11111.0	1	UniProt (Q9D823) Pfam (PF01907)	Mus musculus (house mouse)	60S ribosomal protein L37
39	MA (Lk)	Large ribosomal subunit protein eL38	polymer	70	8224.9	1	UniProt (Q9JJI8) Pfam (PF01781)	Mus musculus (house mouse)	60S ribosomal protein L38
40	NA (Ll)	Large ribosomal subunit protein eL39-like	polymer	51	6355.7	1	UniProt (Q9CQD0) Pfam (PF00832)	Mus musculus (house mouse)	60S ribosomal protein L39-like
41	OA (Lm)	Ubiquitin-ribosomal protein eL40 fusion protein	polymer	128	14758.4	1	UniProt (P62984) Pfam (PF00240) Pfam (PF01020)	Mus musculus (house mouse)	Ubiquitin A-52 residue ribosomal protein fusion product 1
42	PA (Ln)	Small ribosomal subunit protein eS32	polymer	25	3473.5	1	UniProt (P62947) Pfam (PF05162)	Mus musculus (house mouse)	60S ribosomal protein L41,Large ribosomal subunit protein eL41
43	QA (Lo)	Large ribosomal subunit protein eL42	polymer	106	12477.0	1	UniProt (P83882) Pfam (PF00935)	Mus musculus (house mouse)	60S ribosomal protein L36a,60S ribosomal protein L44
44	RA (Lp)	Large ribosomal subunit protein eL43	polymer	92	10299.4	1	UniProt (P61514) Pfam (PF01780)	Mus musculus (house mouse)	60S ribosomal protein L37a
45	SA (Lr)	Large ribosomal subunit protein eL28	polymer	137	15770.6	1	UniProt (P41105) Pfam (PF01778)	Mus musculus (house mouse)	60S ribosomal protein L28
46	TA (S2)	Mus musculus 18S ribosomal RNA	polymer	1870	603101.9	1		Mus musculus (house mouse)
47	UA, VA (S6, S7)	A/P, P/E tRNA	polymer	75	24231.5	2		Mus musculus (house mouse)
48	WA (SA)	Small ribosomal subunit protein uS2	polymer	295	32867.9	1	UniProt (P14206) Pfam (PF00318) Pfam (PF16122)	Mus musculus (house mouse)	37 kDa laminin receptor precursor,37LRP,37 kDa oncofetal antigen,37/67 kDa laminin receptor,LRP/LR,40S ribosomal protein SA,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,OFA/iLRP
49	XA (SB)	Small ribosomal subunit protein eS1	polymer	264	29942.0	1	UniProt (P97351) Pfam (PF01015)	Mus musculus (house mouse)	40S ribosomal protein S3a,Protein TU-11
50	YA (SC)	Small ribosomal subunit protein uS5	polymer	293	31283.4	1	UniProt (P25444) Pfam (PF00333) Pfam (PF03719)	Mus musculus (house mouse)	40S ribosomal protein S2,40S ribosomal protein S4,Protein LLRep3
51	ZA (SD)	Small ribosomal subunit protein uS3	polymer	243	26715.3	1	UniProt (P62908) Pfam (PF07650) Pfam (PF00189)	Mus musculus (house mouse)	40S ribosomal protein S3
52	AB (SE)	Small ribosomal subunit protein eS4	polymer	263	29654.9	1	UniProt (P62702) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121)	Mus musculus (house mouse)	40S ribosomal protein S4,X isoform
53	BB (SF)	Small ribosomal subunit protein uS7	polymer	204	22913.5	1	UniProt (P97461) Pfam (PF00177)	Mus musculus (house mouse)	40S ribosomal protein S5
54	CB (SG)	Small ribosomal subunit protein eS6	polymer	249	28751.9	1	UniProt (P62754) Pfam (PF01092)	Mus musculus (house mouse)	40S ribosomal protein S6,Phosphoprotein NP33
55	DB (SH)	Small ribosomal subunit protein eS7	polymer	194	22168.9	1	UniProt (P62082) Pfam (PF01251)	Mus musculus (house mouse)	40S ribosomal protein S7
56	EB (SI)	Small ribosomal subunit protein eS8	polymer	208	24263.4	1	UniProt (P62242) Pfam (PF01201)	Mus musculus (house mouse)	40S ribosomal protein S8
57	FB (SJ)	Small ribosomal subunit protein uS4	polymer	194	22641.6	1	UniProt (Q6ZWN5) Pfam (PF00163) Pfam (PF01479)	Mus musculus (house mouse)	40S ribosomal protein S9
58	GB (SK)	Small ribosomal subunit protein eS10	polymer	165	18951.8	1	UniProt (P63325) Pfam (PF03501)	Mus musculus (house mouse)	40S ribosomal protein S10
59	HB (SL)	Small ribosomal subunit protein uS17	polymer	158	18468.8	1	UniProt (P62281) Pfam (PF16205) Pfam (PF00366)	Mus musculus (house mouse)	40S ribosomal protein S11
60	IB (SN)	Small ribosomal subunit protein uS15	polymer	151	17259.4	1	UniProt (P62301) Pfam (PF08069) Pfam (PF00312)	Mus musculus (house mouse)	40S ribosomal protein S13
61	JB (SO)	Small ribosomal subunit protein uS11	polymer	151	16302.8	1	UniProt (P62264) Pfam (PF00411)	Mus musculus (house mouse)	40S ribosomal protein S14
62	KB (SP)	Small ribosomal subunit protein uS19	polymer	145	17076.2	1	UniProt (P62843) Pfam (PF00203)	Mus musculus (house mouse)	40S ribosomal protein S15,RIG protein
63	LB (SQ)	Small ribosomal subunit protein uS9	polymer	146	16477.4	1	UniProt (P14131) Pfam (PF00380)	Mus musculus (house mouse)	40S ribosomal protein S16
64	MB (SR)	Small ribosomal subunit protein eS17	polymer	135	15552.1	1	UniProt (P63276) Pfam (PF00833)	Mus musculus (house mouse)	40S ribosomal protein S17
65	NB (SS)	Small ribosomal subunit protein uS13	polymer	152	17759.8	1	UniProt (P62270) Pfam (PF00416)	Mus musculus (house mouse)	40S ribosomal protein S18,Ke-3,Ke3
66	OB (ST)	Small ribosomal subunit protein eS19	polymer	145	16117.6	1	UniProt (Q9CZX8) Pfam (PF01090)	Mus musculus (house mouse)	40S ribosomal protein S19
67	PB (SU)	Small ribosomal subunit protein uS10	polymer	119	13398.8	1	UniProt (P60867) Pfam (PF00338)	Mus musculus (house mouse)	40S ribosomal protein S20
68	QB (SV)	Small ribosomal subunit protein eS21	polymer	83	9154.4	1	UniProt (Q9CQR2) Pfam (PF01249)	Mus musculus (house mouse)	40S ribosomal protein S21
69	RB (SW)	Small ribosomal subunit protein uS8	polymer	130	14865.6	1	UniProt (P62245) Pfam (PF00410)	Mus musculus (house mouse)	40S ribosomal protein S15a
70	SB (SX)	Small ribosomal subunit protein uS12	polymer	143	15844.7	1	UniProt (P62267) Pfam (PF00164)	Mus musculus (house mouse)	40S ribosomal protein S23
71	TB (SY)	Small ribosomal subunit protein eS24	polymer	133	15463.3	1	UniProt (P62849) Pfam (PF01282)	Mus musculus (house mouse)	40S ribosomal protein S24
72	UB (SZ)	Small ribosomal subunit protein eS25	polymer	125	13776.2	1	UniProt (P62852) Pfam (PF03297)	Mus musculus (house mouse)	40S ribosomal protein S25
73	VB (Sa)	Small ribosomal subunit protein eS26	polymer	115	13047.5	1	UniProt (P62855) Pfam (PF01283)	Mus musculus (house mouse)	40S ribosomal protein S26
74	WB (Sb)	Small ribosomal subunit protein eS27	polymer	84	9480.2	1	UniProt (Q6ZWU9) Pfam (PF01667)	Mus musculus (house mouse)	40S ribosomal protein S27
75	XB (Sc)	Small ribosomal subunit protein eS28	polymer	69	7855.1	1	UniProt (P62858) Pfam (PF01200)	Mus musculus (house mouse)	40S ribosomal protein S28
76	YB (Sd)	Small ribosomal subunit protein uS14	polymer	56	6690.8	1	UniProt (P62274) Pfam (PF00253)	Mus musculus (house mouse)	40S ribosomal protein S29
77	ZB (Se)	Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein	polymer	133	14441.7	1	UniProt (P62862) Pfam (PF00240) Pfam (PF04758)	Mus musculus (house mouse)	FAU ubiquitin-like and ribosomal protein S30
78	AC (Sg)	Small ribosomal subunit protein RACK1	polymer	317	35115.7	1	UniProt (P68040) Pfam (PF00400)	Mus musculus (house mouse)	12-3,Guanine nucleotide-binding protein subunit beta-2-like 1,Receptor for activated C kinase,Receptor of activated protein C kinase 1,Receptor of activated protein kinase C 1,p205
79	BC (Sx)	RNA (5'-R(P*AP*UP*CP*AP*UP*GP*AP*AP*GP*U)-3')	polymer	10	3186.0	1		Mus musculus (house mouse)
80	CC (Z)	Nascent peptide	polymer	18	1549.9	1		Mus musculus (house mouse)
81	AD, AE, AF, BD, BE... (L5, L7, LN, LP)	MAGNESIUM ION	non-polymer		24.3	97	Chemie (MG) PubChem (888)
82	WF, XF, YF (Lj, Lm, Lp)	ZINC ION	non-polymer		65.4	3	Chemie (ZN) PubChem (32051)

Contents of the asymmetric unit

Polymers	Number of chains	81
	Total formula weight	3701890.7
Non-Polymers*	Number of molecules	100
	Total formula weight	2553.8
All*	Total formula weight	3704444.5

*Water molecules are not included.