6QD5
X-ray Structure of the Human Urea Channel SLC14A1/UT1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Urea transporter 1 | polymer | 367 | 40177.4 | 1 | UniProt (Q13336) Pfam (PF03253) In PDB | Homo sapiens (Human) | Solute carrier family 14 member 1,Urea transporter,erythrocyte |
2 | A | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 7 | Chemie (BOG) | |||
3 | A | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) | |||
4 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
5 | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 31 - 389 (UniProt: Q13336)
PDB | External Database | Details |
---|---|---|
Met 30 | - | initiating methionine |
Val 167 | Met 167 | variant |
Gln 211 | Asn 211 | engineered mutation |
Asn 280 | Asp 280 | variant |
Ala 390 | - | expression tag |
Glu 391 | - | expression tag |
Asn 392 | - | expression tag |
Leu 393 | - | expression tag |
Tyr 394 | - | expression tag |
Phe 395 | - | expression tag |
Gln 396 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40177.4 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 2921.8 | |
All* | Total formula weight | 43099.2 |