6OKK
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 18S ribosomal RNA | polymer | 2092 | 671337.5 | 1 | Plasmodium falciparum (isolate 3D7) | ||
| 2 | B | 40S ribosomal protein S3a | polymer | 262 | 30111.7 | 1 | UniProt (O97313) Pfam (PF01015) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 3 | C | 40S ribosomal protein SA | polymer | 263 | 29891.2 | 1 | UniProt (Q8IJD4) Pfam (PF00318) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 4 | D | 40S ribosomal protein S3 | polymer | 221 | 24709.9 | 1 | UniProt (Q8IKH8) Pfam (PF07650) Pfam (PF00189) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 5 | E | 40S ribosomal protein S9 | polymer | 189 | 22172.1 | 1 | UniProt (Q8I3R0) Pfam (PF00163) Pfam (PF01479) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 6 | F | 40S ribosomal protein S4 | polymer | 261 | 29830.3 | 1 | UniProt (Q8IIU8) Pfam (PF00467) Pfam (PF16121) Pfam (PF08071) Pfam (PF00900) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 7 | G | 40S ribosomal protein S5 | polymer | 272 | 30008.8 | 1 | UniProt (Q8IL02) Pfam (PF00333) Pfam (PF03719) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 8 | H | 40S ribosomal protein S6 | polymer | 306 | 35473.8 | 1 | UniProt (Q8IDR9) Pfam (PF01092) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 9 | I | 40S ribosomal protein S5 | polymer | 195 | 21898.5 | 1 | UniProt (Q8IBN5) Pfam (PF00177) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 10 | J | 40S ribosomal protein S7 | polymer | 194 | 22524.7 | 1 | UniProt (Q8IET7) Pfam (PF01251) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 11 | K | 40S ribosomal protein S15A | polymer | 130 | 14900.7 | 1 | UniProt (O77395) Pfam (PF00410) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 12 | L | 40S ribosomal protein S8 | polymer | 218 | 25106.0 | 1 | UniProt (Q8IM10) Pfam (PF01201) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 13 | M | 40S ribosomal protein S16 | polymer | 144 | 16318.2 | 1 | UniProt (A0A0L7M7C8) Pfam (PF00380) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 14 | N | 40S ribosomal protein S20e | polymer | 118 | 13534.9 | 1 | UniProt (Q8IK02) Pfam (PF00338) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 15 | O | 40S ribosomal protein S10 | polymer | 137 | 16510.2 | 1 | UniProt (Q8IBQ5) Pfam (PF03501) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 16 | P | 40S ribosomal protein S11 | polymer | 151 | 16105.6 | 1 | UniProt (Q8I3U6) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 17 | Q | 40S ribosomal protein S23 | polymer | 145 | 16167.0 | 1 | UniProt (O97248) Pfam (PF00164) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 18 | R | 40S ribosomal protein S12 | polymer | 141 | 15414.4 | 1 | UniProt (O97249) Pfam (PF01248) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 19 | S | 40S ribosomal protein S18 | polymer | 156 | 17928.9 | 1 | UniProt (Q8IIA2) Pfam (PF00416) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 20 | T | 40S ribosomal protein S29 | polymer | 54 | 6430.7 | 1 | UniProt (C0H4K8) Pfam (PF00253) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 21 | U | 40S ribosomal protein S15 | polymer | 151 | 17286.5 | 1 | UniProt (Q8IDB0) Pfam (PF08069) Pfam (PF00312) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 22 | V | 40S ribosomal protein S11 | polymer | 161 | 18801.2 | 1 | UniProt (O77381) Pfam (PF16205) Pfam (PF00366) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 23 | W | 40S ribosomal protein S17 | polymer | 137 | 16097.0 | 1 | UniProt (Q8I502) Pfam (PF00833) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 24 | X | 40S ribosomal protein S19 | polymer | 145 | 16800.8 | 1 | UniProt (C0H5C2) Pfam (PF00203) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 25 | Y | 40S ribosomal protein S19 | polymer | 170 | 19757.9 | 1 | UniProt (Q8IFP2) Pfam (PF01090) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 26 | Z | 40S ribosomal protein S21 | polymer | 82 | 9157.5 | 1 | UniProt (Q8IHS5) Pfam (PF01249) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 27 | a | 40S ribosomal protein S24 | polymer | 133 | 15431.5 | 1 | UniProt (Q8I3R6) Pfam (PF01282) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 28 | b | 40S ribosomal protein S25 | polymer | 105 | 11691.9 | 1 | UniProt (Q8ILN8) Pfam (PF03297) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 29 | c | 40S ribosomal protein S26 | polymer | 107 | 12539.7 | 1 | UniProt (O96258) Pfam (PF01283) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 30 | d | 40S ribosomal protein S27 | polymer | 82 | 9154.9 | 1 | UniProt (Q8IEN2) Pfam (PF01667) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 31 | e | 40S ribosomal protein S28e | polymer | 67 | 7508.8 | 1 | UniProt (Q8IKL9) Pfam (PF01200) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 32 | f | 40S ribosomal protein S30 | polymer | 58 | 6508.7 | 1 | UniProt (O96269) Pfam (PF04758) In PDB | Plasmodium falciparum (isolate 3D7) | |
| 33 | g | E-site tRNA | polymer | 74 | 23774.1 | 1 | Plasmodium falciparum (isolate 3D7) | ||
| 34 | A | MAGNESIUM ION | non-polymer | 24.3 | 67 | Chemie (MG) | |||
| 35 | P | emetine | non-polymer | 480.6 | 1 | Chemie (34G) | |||
| 36 | T | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 33 |
| Total formula weight | 1260885.4 | |
| Non-Polymers* | Number of molecules | 69 |
| Total formula weight | 2174.5 | |
| All* | Total formula weight | 1263059.9 |
