6NJE

Crystal structure of the motor domain of human kinesin family member 22

Replaces:  3BFN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Kinesin-like protein KIF22	polymer	379	42132.8	1	UniProt (Q14807) Pfam (PF00225) In PDB	Homo sapiens (Human)	Kinesin-like DNA-binding protein,Kinesin-like protein 4
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
4	A	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
5	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6		water	water		18.0	90	Chemie (HOH)

Sequence modifications

A: 40 - 400 (UniProt: Q14807)

PDB	External Database	Details
Met 22	-	initiating methionine
His 23	-	expression tag
His 24	-	expression tag
His 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
Ser 29	-	expression tag
Ser 30	-	expression tag
Gly 31	-	expression tag
Arg 32	-	expression tag
Glu 33	-	expression tag
Asn 34	-	expression tag
Leu 35	-	expression tag
Tyr 36	-	expression tag
Phe 37	-	expression tag
Gln 38	-	expression tag
Gly 39	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42132.8
Non-Polymers*	Number of molecules	6
	Total formula weight	580.9
All*	Total formula weight	42713.7

*Water molecules are not included.