6HT1

Crystal structure of MLLT1 (ENL) YEATS domain in complexed with SGC-iMLLT (compound 92)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein ENL	polymer	155	18312.1	1	UniProt (Q03111) Pfam (PF03366) In PDB	Homo sapiens (Human)	YEATS domain-containing protein 1
2	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	7	Chemie (EDO)
4	A	1-methyl-~{N}-[2-[[(2~{S})-2-methylpyrrolidin-1-yl]methyl]-3~{H}-benzimidazol-5-yl]indazole-5-carboxamide	non-polymer		388.5	1	Chemie (GQ5)
5		water	water		18.0	51	Chemie (HOH)

Sequence modifications

A: 1 - 148 (UniProt: Q03111)

PDB	External Database	Details
Ser 0	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	18312.1
Non-Polymers*	Number of molecules	10
	Total formula weight	1015.1
All*	Total formula weight	19327.1

*Water molecules are not included.