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6FR0

Crystal structure of CREBBP bromodomain complexd with PB08

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BCREB-binding proteinpolymer11914223.32UniProt (Q92793)
Pfam (PF00439)
In PDB
Homo sapiens (Human)
2A, B~{N}-[3-(5-ethanoyl-2-ethoxy-phenyl)-5-(2-ethyl-5-methyl-3-oxidanylidene-1,2-oxazol-4-yl)phenyl]furan-2-carboxamidenon-polymer474.52Chemie (E3H)
3waterwater18.0181Chemie (HOH)
Sequence modifications
A, B: 1081 - 1197 (UniProt: Q92793)
PDBExternal DatabaseDetails
Ser 1079-expression tag
Met 1080-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28446.7
Non-Polymers*Number of molecules2
Total formula weight949.0
All*Total formula weight29395.7
*Water molecules are not included.

217705

數據於2024-03-27公開中

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