6EQV
X-ray structure of the proprotein convertase furin bound with the competitive inhibitor Phac-Cit-Val-Arg-Amba
エンティティ
| Entity ID | 鎖名 | 説明 | 種類 | 鎖長 | 化学式量 | 分子数 | データベース名(アクセス番号) | 由来する生物種 | エンティティの一般名 |
| 1 | A | Furin | polymer | 482 | 52388.6 | 1 | UniProt (P09958) Pfam (PF00082) Pfam (PF01483) In PDB | Homo sapiens (Human) | Dibasic-processing enzyme,Paired basic amino acid residue-cleaving enzyme,PACE |
| 2 | D | HY1-LLI-VAL-ARG-00S | polymer | 5 | 664.8 | 1 | synthetic construct | ||
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 510 | Chemie (HOH) |
配列変更
A: 108 - 574 (UniProt: P09958)
| PDB | 外部データベース | 詳細 |
|---|---|---|
| Ser 575 | - | expression tag |
| Gly 576 | - | expression tag |
| Ser 577 | - | expression tag |
| Leu 578 | - | expression tag |
| Val 579 | - | expression tag |
| Pro 580 | - | expression tag |
| Arg 581 | - | expression tag |
| Gly 582 | - | expression tag |
| Ser 583 | - | expression tag |
| His 584 | - | expression tag |
| His 585 | - | expression tag |
| His 586 | - | expression tag |
| His 587 | - | expression tag |
| His 588 | - | expression tag |
| His 589 | - | expression tag |
配列ビューア
非対称単位の内容
| タンパク質・ 核酸鎖 | 鎖の数 | 2 |
| 化学式量合計 | 53053.4 | |
| タンパク質・ 核酸・ 糖鎖以外* | 分子数 | 8 |
| 化学式量合計 | 247.6 | |
| 全て* | 化学式量合計 | 53301.1 |
