6E4X

Human antibody S5V2-29 in complex with influenza hemagglutinin A/Texas/50/2012 (H3N2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	Hemagglutinin	polymer	291	32618.8	1	UniProt (R4L1D1) Pfam (PF00509) In PDB	Influenza A virus (A/Texas/50/2012(H3N2))
2	Y	S5V2-29 light chain	polymer	210	22803.2	1	UniProt (Q8TCD0) Pfam (PF07686) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	Z	S5V2-29 heavy chain	polymer	241	25984.3	1		Homo sapiens (Human)
4	A	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	1	In PDB GlyTouCan (G42466VF)
5	C	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
6	D	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G18638YB)
7	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
8	B, Y	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
9		water	water		18.0	144	Chemie (HOH)

Sequence modifications

B: 37 - 319 (UniProt: R4L1D1)

PDB	External Database	Details
Gly 320	-	expression tag
Ala 321	-	expression tag
Leu 322	-	expression tag
Glu 323	-	expression tag
Val 324	-	expression tag
Leu 325	-	expression tag
Phe 326	-	expression tag
Gln 327	-	expression tag

Y: 1 - 92 (PDB: 6E4X)
Y: 93 - 210 (UniProt: Q8TCD0)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	81406.3
Branched	Number of molecules	3
	Total formula weight	2214.0
Non-Polymers*	Number of molecules	5
	Total formula weight	589.6
All*	Total formula weight	84209.9

*Water molecules are not included.