6DXK
Glucocorticoid Receptor in complex with Compound 11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glucocorticoid receptor | polymer | 258 | 29667.3 | 2 | UniProt (P04150) Pfam (PF00104) In PDB | Homo sapiens (Human) | GR,Nuclear receptor subfamily 3 group C member 1 |
| 2 | A, B | (8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-(3,3-dimethylbut-1-yn-1-yl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name) | non-polymer | 471.7 | 2 | Chemie (HJ4) | |||
| 3 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B: 522 - 777 (UniProt: P04150)
| PDB | External Database | Details |
|---|---|---|
| Ser 520 | - | expression tag |
| Ser 521 | - | expression tag |
| Ser 525 | Leu 526 | variant |
| Ser 528 | Leu 529 | variant |
| Ala 535 | Leu 536 | variant |
| Thr 538 | Val 539 | variant |
| Tyr 602 | Phe 603 | variant |
| Asp 638 | Cys 639 | variant |
| Ala 684 | Glu 685 | variant |
| Ala 688 | Glu 689 | variant |
| Ser 712 | Trp 713 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59334.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 943.3 | |
| All* | Total formula weight | 60278.0 |
