5ZHX
Crystal structure of SmgGDS-558 and farnesylated RhoA complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Rap1 GTPase-GDP dissociation stimulator 1 | polymer | 487 | 53418.9 | 4 | UniProt (P52306) Pfam (PF00514) In PDB | Homo sapiens (Human) | Exchange factor smgGDS,SMG GDS protein,SMG P21 stimulatory GDP/GTP exchange protein |
2 | e, f, g, h | Transforming protein RhoA | polymer | 198 | 22168.5 | 4 | UniProt (P61586) Pfam (PF00071) In PDB | Homo sapiens (Human) | Rho cDNA clone 12,h12 |
3 | e, f, g, h | FARNESYL | non-polymer | 206.4 | 4 | Chemie (FAR) |
Sequence modifications
A, B, C, D: 77 - 558 (UniProt: P52306)
e, f, g, h: 1 - 193 (UniProt: P61586)
PDB | External Database | Details |
---|---|---|
Gly 72 | - | expression tag |
Pro 73 | - | expression tag |
Leu 74 | - | expression tag |
Gly 75 | - | expression tag |
Ser 76 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Leu -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Ala 193 | Leu 193 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 302349.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 825.5 | |
All* | Total formula weight | 303175.4 |