5YQZ
Structure of the glucagon receptor in complex with a glucagon analogue
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | R | Glucagon receptor,Endolysin,Glucagon receptor | polymer | 575 | 65799.1 | 1 | UniProt (P47871) UniProt (D9IEF7) Pfam (PF02793) Pfam (PF00002) Pfam (PF00959) UniProt (by SIFTS) (P00720) In PDB | Homo sapiens (Human) | GL-R,Lysis protein,Lysozyme,Muramidase |
2 | P | Glucagon analogue | polymer | 28 | 3345.7 | 1 | Pfam (PF00123) UniProt (by SIFTS) (P01275) In PDB | Homo sapiens | |
3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
4 | R | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 6 | Chemie (OLC) | |||
5 | R | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) |
Sequence modifications
R: 27 - 257 (UniProt: P47871)
R: 1001 - 1160 (UniProt: D9IEF7)
R: 260 - 432 (UniProt: P47871)
PDB | External Database | Details |
---|---|---|
Gly 24 | - | expression tag |
Ala 25 | - | expression tag |
Pro 26 | - | expression tag |
Ala 173 | Arg 173 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Thr 1053 | Cys 54 | engineered mutation |
Ala 1096 | Cys 97 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Glu 433 | - | expression tag |
Phe 434 | - | expression tag |
Leu 435 | - | expression tag |
Glu 436 | - | expression tag |
Val 437 | - | expression tag |
Leu 438 | - | expression tag |
Phe 439 | - | expression tag |
Gln 440 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 69144.7 | |
Branched | Number of molecules | 2 |
Total formula weight | 848.8 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 2234.2 | |
All* | Total formula weight | 72227.7 |