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5YQZ

Structure of the glucagon receptor in complex with a glucagon analogue

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1RGlucagon receptor,Endolysin,Glucagon receptorpolymer57565799.11UniProt (P47871)
UniProt (D9IEF7)
Pfam (PF02793)
Pfam (PF00002)
Pfam (PF00959)
UniProt (by SIFTS) (P00720)
In PDB
Homo sapiens (Human)GL-R,Lysis protein,Lysozyme,Muramidase
2PGlucagon analoguepolymer283345.71Pfam (PF00123)
UniProt (by SIFTS) (P01275)
In PDB
Homo sapiens
3A, B2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
4R(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoatenon-polymer356.56Chemie (OLC)
5RPHOSPHATE IONnon-polymer95.01Chemie (PO4)
Sequence modifications
R: 27 - 257 (UniProt: P47871)
PDBExternal DatabaseDetails
Gly 24-expression tag
Ala 25-expression tag
Pro 26-expression tag
Ala 173Arg 173engineered mutation
R: 1001 - 1160 (UniProt: D9IEF7)
PDBExternal DatabaseDetails
Thr 1053Cys 54engineered mutation
Ala 1096Cys 97engineered mutation
R: 260 - 432 (UniProt: P47871)
PDBExternal DatabaseDetails
Glu 433-expression tag
Phe 434-expression tag
Leu 435-expression tag
Glu 436-expression tag
Val 437-expression tag
Leu 438-expression tag
Phe 439-expression tag
Gln 440-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight69144.7
BranchedNumber of molecules2
Total formula weight848.8
Non-Polymers*Number of molecules7
Total formula weight2234.2
All*Total formula weight72227.7
*Water molecules are not included.

217705

数据于2024-03-27公开中

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