5YKP
Human methionine aminopeptidase type 1b (F309M mutant) in complex with ovalicin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Methionine aminopeptidase 1 | polymer | 305 | 34260.0 | 1 | UniProt (P53582) Pfam (PF00557) In PDB | Homo sapiens (Human) | MetAP 1,Peptidase M 1 |
| 2 | A | COBALT (II) ION | non-polymer | 58.9 | 3 | Chemie (CO) | |||
| 3 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 4 | A | 3,4-DIHYDROXY-2-METHOXY-4-METHYL-3-[2-METHYL-3-(3-METHYL-BUT-2-ENYL) -OXIRANYL]-CYCLOHEXANONE | non-polymer | 298.4 | 1 | Chemie (OVA) | |||
| 5 | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A: 90 - 393 (UniProt: P53582)
| PDB | External Database | Details |
|---|---|---|
| Pro 89 | - | expression tag |
| Met 309 | Phe 300 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34260.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 514.3 | |
| All* | Total formula weight | 34774.3 |
