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5PZU

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor [5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DFructose-1,6-bisphosphatase 1polymer33836859.44UniProt (Q2TU34)
Pfam (PF00316)
Pfam (PF18913)
UniProt (by SIFTS) (P09467)
In PDB
Homo sapiens (Human)Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA
2A, B, C, D{5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl}phosphonic acidnon-polymer302.34Chemie (94D)
3waterwater18.01386Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight147437.7
Non-Polymers*Number of molecules4
Total formula weight1209.1
All*Total formula weight148646.8
*Water molecules are not included.

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PDB entries from 2024-04-17

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