5PZR

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(3-chlorophenyl)sulfonyl-3-[3-[3-[(3-chlorophenyl)sulfonylcarbamoylamino]propoxy]propyl]urea

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
A, B, C, DFructose-1,6-bisphosphatase 1polymer33836859.44
UniProt (Q2TU34)
Pfam (PF00316)
Homo sapiens (Human)Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA
N,N'-{oxybis[(propane-3,1-diyl)carbamoyl]}bis(3-chlorobenzene-1-sulfonamide)non-polymer567.52
waterwater18.01204

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains4
Total molecular weight147437.7
Non-Polymers*Number of molecules2
Total molecular weight1134.9
All*Total molecular weight148572.6
*Water molecules are not included.