5CUQ

Identification and characterization of novel broad spectrum inhibitors of the flavivirus methyltransferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Nonstructural protein NS5	polymer	267	30069.6	2	UniProt (C0LMU0) Pfam (PF01728) In PDB	Dengue virus 3
2	A, B	N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA	non-polymer		372.4	2	Chemie (NSC)
3		water	water		18.0	500	Chemie (HOH)

Sequence modifications

A, B: 1 - 262 (UniProt: C0LMU0)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	60139.2
Non-Polymers*	Number of molecules	2
	Total formula weight	744.8
All*	Total formula weight	60884.0

*Water molecules are not included.