5ANR

Structure of a human 4E-T - DDX6 - CNOT1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1	polymer	258	29695.4	1	UniProt (A5YKK6) Pfam (PF16415) In PDB	HOMO SAPIENS (HUMAN)	CCR4-ASSOCIATED FACTOR 1, NOT1H, NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1 HOMOLOG, HNOT1, CNOT1-MIF4G DOMAIN
2	B	PROBABLE ATP-DEPENDENT RNA HELICASE DDX6	polymer	378	43189.2	1	UniProt (P26196) Pfam (PF00270) Pfam (PF00271) In PDB	HOMO SAPIENS (HUMAN)	ATP-DEPENDENT RNA HELICASE P54, DEAD BOX PROTEIN 6, ONCOGENE RCK, DDX6
3	C	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER	polymer	44	5092.4	1	UniProt (Q9NRA8) In PDB	HOMO SAPIENS (HUMAN)	4E-T, EIF4E TRANSPORTER, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E NUCLEAR IMPORT FACTOR 1,4ET
4		water	water		18.0	276	Chemie (HOH)

Sequence modifications

A: 1058 - 1309 (UniProt: A5YKK6)

PDB	External Database	Details
Gln 1052	-	expression tag
Gly 1053	-	expression tag
Pro 1054	-	expression tag
Asp 1055	-	expression tag
Ser 1056	-	expression tag
Met 1057	-	expression tag

B: 95 - 469 (UniProt: P26196)

PDB	External Database	Details
Arg 92	-	expression tag
Ser 93	-	expression tag
Met 94	-	expression tag

C: 199 - 239 (UniProt: Q9NRA8)

PDB	External Database	Details
Arg 196	-	expression tag
Ser 197	-	expression tag
Met 198	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	77976.9
All*	Total formula weight	77976.9

*Water molecules are not included.