4UO6

Structure of the A_Canine_Colorado_17864_06 H3 haemagglutinin in complex with Sialyl Lewis X

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	H3 HAEMAGGLUTININ HA1 CHAIN	polymer	328	36346.0	1	UniProt (E0UVR5) Pfam (PF00509) In PDB	INFLUENZA A VIRUS (A/CANINE/COLORADO/17864/2006(H3N8))	HEMAGGLUTININ
2	B	H3 HAEMAGGLUTININ HA2 CHAIN	polymer	175	20273.4	1	UniProt (E0UVR5) Pfam (PF00509) In PDB	INFLUENZA A VIRUS (A/CANINE/COLORADO/17864/2006(H3N8))	HEMAGGLUTININ
3	C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	D	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	E	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
6	F	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		820.7	1	In PDB BIRD (PRD_900121) GlyTouCan (G00054MO)		Sialyl-Lewis X antigen, beta anomer
7	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
8	A, B	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
9		water	water		18.0	47	Chemie (HOH)

Sequence modifications

B: 1 - 172 (UniProt: E0UVR5)

PDB	External Database	Details
Ser 173	-	expression tag
Gly 174	-	expression tag
Arg 175	-	expression tag
Glu 131	Asp 475	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56619.4
Branched	Number of molecules	4
	Total formula weight	2742.5
Non-Polymers*	Number of molecules	5
	Total formula weight	730.6
All*	Total formula weight	60092.5

*Water molecules are not included.