4UE7

Thrombin in complex with 1-amidinopiperidine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	THROMBIN HEAVY CHAIN	polymer	258	29651.1	1	UniProt (P00734) Pfam (PF00089) In PDB	HOMO SAPIENS (HUMAN)	PROTHROMBIN, COAGULATION FACTOR II, ACTIVATION PEPTIDE FRAGMENT 1, ACTIVATION PEPTIDE FRAGMENT 2, THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN
2	I	HIRUDIN VARIANT-2	polymer	12	1548.6	1	UniProt (P09945) In PDB	HIRUDO MEDICINALIS
3	L	THROMBIN LIGHT CHAIN	polymer	28	3317.7	1	UniProt (P00734) Pfam (PF09396) In PDB	HOMO SAPIENS (HUMAN)	PROTHROMBIN, COAGULATION FACTOR II, ACTIVATION PEPTIDE FRAGMENT 1, ACTIVATION PEPTIDE FRAGMENT 2
4	H	IODIDE ION	non-polymer		126.9	1	Chemie (IOD)
5	H	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
6	H	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
7	H	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
8	H	DIMETHYL SULFOXIDE	non-polymer		78.1	3	Chemie (DMS)
9	H	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
10	H	piperidine-1-carboximidamide	non-polymer		127.2	1	Chemie (MRZ)
11	H	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
12		water	water		18.0	322	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	34517.4
Non-Polymers*	Number of molecules	13
	Total formula weight	1189.0
All*	Total formula weight	35706.4

*Water molecules are not included.