4ORC
Crystal structure of mammalian calcineurin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | polymer | 544 | 61264.5 | 1 | UniProt (P16298) Pfam (PF00149) In PDB | Homo sapiens (human) | CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit beta isoform |
| 2 | B | Calcineurin subunit B type 1 | polymer | 170 | 19322.9 | 1 | UniProt (P63098) Pfam (PF13499) In PDB | Homo sapiens (human) | Protein phosphatase 2B regulatory subunit 1, Protein phosphatase 3 regulatory subunit B alpha isoform 1 |
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 5 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | B | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 7 | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A: 1 - 524 (UniProt: P16298)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80587.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 376.5 | |
| All* | Total formula weight | 80963.9 |
