4NCJ

Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation with ADP Beryllium Flouride

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	DNA double-strand break repair Rad50 ATPase	polymer	339	38580.5	4	UniProt (P58301) Pfam (PF13476) Pfam (PF13304) In PDB	Pyrococcus furiosus
2	A, B, C, D	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	4	Chemie (ADP)
3	A, B, C, D	BERYLLIUM TRIFLUORIDE ION	non-polymer		66.0	4	Chemie (BEF)
4	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5		water	water		18.0	902	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 177 (UniProt: P58301)
A, B, C, D: 726 - 882 (UniProt: P58301)

PDB	External Database	Details
Gly 721	-	linker
Gly 722	-	linker
Ser 723	-	linker
Gly 724	-	linker
Gly 725	-	linker
Glu 805	Arg 805	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	154322.1
Non-Polymers*	Number of molecules	12
	Total formula weight	2070.1
All*	Total formula weight	156392.2

*Water molecules are not included.