4LD9

Crystal structure of the N-terminally acetylated BAH domain of Sir3 bound to the nucleosome core particle

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Histone H3.2	polymer	136	15421.1	2	UniProt (P84233) Pfam (PF00125) In PDB	Xenopus laevis (clawed frog common platanna platanna)
2	B, F	Histone H4	polymer	103	11394.4	2	UniProt (P62799) Pfam (PF15511) In PDB	Xenopus laevis (clawed frog common platanna platanna)
3	C, G	Histone H2A	polymer	130	14109.4	2	UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) In PDB	Xenopus laevis (clawed frog common platanna platanna)
4	D, H	Histone H2B 1.1	polymer	126	13965.3	2	UniProt (P02281) Pfam (PF00125) In PDB	Xenopus laevis (clawed frog common platanna platanna)	H2B1.1
5	I	Widom 601 sequence reverse	polymer	167	51809.0	1
6	J	Widom 601 sequence forward	polymer	167	51341.7	1
7	K, L	Regulatory protein SIR3	polymer	236	28073.9	2	UniProt (P06701) Pfam (PF01426) In PDB	Saccharomyces cerevisiae (Baker's yeast)	Silent information regulator 3

Sequence modifications

K, L: 2 - 229 (UniProt: P06701)

PDB	External Database	Details
Ace 1	-	ACETYLATION
Lys 230	-	EXPRESSION TAG
His 231	-	EXPRESSION TAG
His 232	-	EXPRESSION TAG
His 233	-	EXPRESSION TAG
His 234	-	EXPRESSION TAG
His 235	-	EXPRESSION TAG
His 236	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	269078.9
All*	Total formula weight	269078.9

*Water molecules are not included.