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4H10

Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic Helix-Loop-Helix domains with E-box DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAryl hydrocarbon receptor nuclear translocator-like protein 1polymer738693.21UniProt (O00327)
Pfam (PF00010)
In PDB
Homo sapiens (human)Basic-helix-loop-helix-PAS protein MOP3, Brain and muscle ARNT-like 1, Class E basic helix-loop-helix protein 5, bHLHe5, Member of PAS protein 3, PAS domain-containing protein 3, bHLH-PAS protein JAP3
2BCircadian locomoter output cycles protein kaputpolymer718535.91UniProt (O15516)
Pfam (PF00010)
In PDB
Homo sapiens (human)hCLOCK, Class E basic helix-loop-helix protein 8, bHLHe8
3CE-box DNA sense strandpolymer154588.01
4DE-box DNA antisense strandpolymer154592.01
5waterwater18.0106Chemie (HOH)
Sequence modifications
A: 66 - 128 (UniProt: O00327)
PDBExternal DatabaseDetails
Met 65-expression tag
Trp 129-expression tag
Leu 130-expression tag
Glu 131-expression tag
His 132-expression tag
His 133-expression tag
His 134-expression tag
His 135-expression tag
His 136-expression tag
His 137-expression tag
B: 29 - 89 (UniProt: O15516)
PDBExternal DatabaseDetails
Met 28-expression tag
Trp 90-expression tag
Leu 91-expression tag
Glu 92-expression tag
His 93-expression tag
His 94-expression tag
His 95-expression tag
His 96-expression tag
His 97-expression tag
His 98-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight26409.0
All*Total formula weight26409.0
*Water molecules are not included.

217705

PDB entries from 2024-03-27

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