4GJA

Crystal structure of renin in complex with NVP-AYL747 (compound 5)

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
A, BReninpolymer34037267.02
UniProt (P00797)
Pfam (PF00026)
Homo sapiens (human)@PDBjAngiotensinogenase
N-ACETYL-D-GLUCOSAMINEnon-polymer221.22
(3S,5R)-N-(2,2-diphenylethyl)-5-{[(4-methylphenyl)sulfonyl]amino}piperidine-3-carboxamidenon-polymer477.62
SULFATE IONnon-polymer96.13
waterwater18.0215

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains2
Total molecular weight74534.0
Non-Polymers*Number of molecules7
Total molecular weight1685.8
All*Total molecular weight76219.9
*Water molecules are not included.