4CWT
Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HEAT SHOCK PROTEIN HSP 90-ALPHA | polymer | 230 | 25810.9 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | HOMO SAPIENS (HUMAN) | HEAT SHOCK 86 KDA, HSP 86, HSP86, RENAL CARCINOMA ANTIGEN NY-REN-38 |
| 2 | A | 2-{[(2Z)-5-(1,3-benzodioxol-5-ylmethyl)-8-fluoro-2-imino-2,3-dihydro[1,2,4]triazolo[1,5-c]quinazolin-10-yl]amino}ethanol | non-polymer | 396.4 | 1 | Chemie (IK9) | |||
| 3 | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A: 9 - 236 (UniProt: P07900)
| PDB | External Database | Details |
|---|---|---|
| Gly 7 | - | expression tag |
| Pro 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25810.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 396.4 | |
| All* | Total formula weight | 26207.3 |
