4CBO
Crystal structure of Complement Factor D mutant R202A after ensemble refinement
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | COMPLEMENT FACTOR D | polymer | 228 | 24352.7 | 2 | UniProt (P00746) Pfam (PF00089) In PDB | HOMO SAPIENS (HUMAN) | ADIPSIN, C3 CONVERTASE ACTIVATOR, PROPERDIN FACTOR D |
| 2 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | water | water | 18.0 | 261 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 228 (UniProt: P00746)
| PDB | External Database | Details |
|---|---|---|
| Ala 202 | Arg 227 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48705.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 48889.6 |
