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4C6M

Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 7.0

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACAD PROTEINpolymer39342916.01UniProt (P27708)
Pfam (PF01979)
In PDB
HOMO SAPIENS (HUMAN)DIHYDROOROTASE
2AZINC IONnon-polymer65.43Chemie (ZN)
3AFORMIC ACIDnon-polymer46.02Chemie (FMT)
4A5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACIDnon-polymer174.11Chemie (FOT)
5waterwater18.0385Chemie (HOH)
Sequence modifications
A: 1456 - 1846 (UniProt: P27708)
PDBExternal DatabaseDetails
Gly 1454-expression tag
Pro 1455-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42916.0
Non-Polymers*Number of molecules6
Total formula weight462.4
All*Total formula weight43378.4
*Water molecules are not included.

217705

数据于2024-03-27公开中

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