4A51
Crystal structure of human kinesin Eg5 in complex with 1-(3-(((2-Aminoethyl)thio)diphenylmethyl)phenyl)ethanone hydrochloride
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | KINESIN-LIKE PROTEIN KIF11 | polymer | 368 | 41055.6 | 7 | UniProt (P52732) Pfam (PF00225) In PDB | HOMO SAPIENS (HUMAN) | EG5, KINESIN-LIKE PROTEIN 1, KINESIN-LIKE SPINDLE PROTEIN HKSP, KINESIN-RELATED MOTOR PROTEIN EG5, THYROID RECEPTOR-INTERACTING PROTEIN 5, TR-INTERACTING PROTEIN 5, TRIP-5 |
| 2 | E, A, F, G, B... | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 7 | Chemie (ADP) | |||
| 3 | D, E, A, F, G... | MAGNESIUM ION | non-polymer | 24.3 | 7 | Chemie (MG) | |||
| 4 | D, E, A, F, G... | 1-(3-{[(2-aminoethyl)sulfanyl](diphenyl)methyl}phenyl)ethanone | non-polymer | 361.5 | 7 | Chemie (DQ8) | |||
| 5 | D, E, A, F, G... | CHLORIDE ION | non-polymer | 35.5 | 14 | Chemie (CL) | |||
| 6 | D | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 287389.1 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 6283.4 | |
| All* | Total formula weight | 293672.5 |
