3P5J
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ribonuclease H2 subunit A | polymer | 301 | 33547.7 | 1 | UniProt (Q9CWY8) Pfam (PF01351) In PDB | Mus musculus (mouse) | RNase H2 subunit A, Ribonuclease HI large subunit, RNase HI large subunit, Ribonuclease HI subunit A |
2 | B | Ribonuclease H2 subunit B | polymer | 332 | 37494.1 | 1 | UniProt (Q80ZV0) Pfam (PF17745) Pfam (PF09468) In PDB | Mus musculus (mouse) | RNase H2 subunit B, Deleted in lymphocytic leukemia 8 homolog, Ribonuclease HI subunit B |
3 | C | Ribonuclease H2 subunit C | polymer | 166 | 17848.1 | 1 | UniProt (Q9CQ18) Pfam (PF08615) In PDB | Mus musculus (mouse) | RNase H2 subunit C, Ribonuclease HI subunit C |
Sequence modifications
B: 1 - 308 (UniProt: Q80ZV0)
PDB | External Database | Details |
---|---|---|
Met -23 | - | expression tag |
Gly -22 | - | expression tag |
Ser -21 | - | expression tag |
Ser -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
Ser -13 | - | expression tag |
Gln -12 | - | expression tag |
Asp -11 | - | expression tag |
Pro -10 | - | expression tag |
Asn -9 | - | expression tag |
Ser -8 | - | expression tag |
Leu -7 | - | expression tag |
Glu -6 | - | expression tag |
Val -5 | - | expression tag |
Leu -4 | - | expression tag |
Phe -3 | - | expression tag |
Gln -2 | - | expression tag |
Gly -1 | - | expression tag |
Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 88889.9 | |
All* | Total formula weight | 88889.9 |