3M0D

Crystal structure of the TRAF1:TRAF2:cIAP2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	TNF receptor-associated factor 2	polymer	66	7572.6	2	UniProt (Q12933) Pfam (PF16673) In PDB	Homo sapiens (human)	Tumor necrosis factor type 2 receptor-associated protein 3
2	C	TNF receptor-associated factor 1	polymer	65	7468.7	1	UniProt (Q13077) Pfam (PF16673) In PDB	Homo sapiens (human)	Epstein-Barr virus-induced protein 6
3	D	Baculoviral IAP repeat-containing protein 3	polymer	75	8582.0	1	UniProt (Q13489) Pfam (PF00653) In PDB	Homo sapiens (human)	Inhibitor of apoptosis protein 1, IAP-1, hIAP-1, hIAP1, C-IAP2, TNFR2-TRAF-signaling complex protein 1, IAP homolog C, Apoptosis inhibitor 2, API2, RING finger protein 49
4	D	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
5		water	water		18.0	42	Chemie (HOH)

Sequence modifications

A, B: 266 - 329 (UniProt: Q12933)

PDB	External Database	Details
Leu 330	-	expression tag
Glu 331	-	expression tag

C: 266 - 329 (UniProt: Q13077)

PDB	External Database	Details
Met 265	-	initiating methionine

D: 26 - 99 (UniProt: Q13489)

PDB	External Database	Details
Met 25	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	31195.9
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	31261.3

*Water molecules are not included.