3FEX
Crystal structure of the CBC-importin alpha complex.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Nuclear cap-binding protein subunit 1 | polymer | 790 | 91960.3 | 1 | UniProt (Q09161) Pfam (PF02854) Pfam (PF09088) Pfam (PF09090) In PDB | Homo sapiens (human) | Cap binding protein 80; 80 kDa nuclear cap-binding protein; NCBP 80 kDa subunit; CBP80 |
2 | B | Nuclear cap-binding protein subunit 2 | polymer | 156 | 18028.1 | 1 | UniProt (P52298) Pfam (PF00076) In PDB | Homo sapiens (human) | Cap binding protein 20; 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20, NCBP-interacting protein 1, NIP1, Cell proliferation-inducing gene 55 protein |
3 | C | Importin subunit alpha-2 | polymer | 467 | 50779.5 | 1 | UniProt (P52292) Pfam (PF00514) Pfam (PF16186) Pfam (PF01749) In PDB | Homo sapiens (human) | Importin alpha 1; Karyopherin subunit alpha-2, SRP1-alpha, RAG cohort protein 1 |
Sequence modifications
C: 70 - 529 (UniProt: P52292)
PDB | External Database | Details |
---|---|---|
Met 69 | - | expression tag |
His 530 | - | expression tag |
His 531 | - | expression tag |
His 532 | - | expression tag |
His 533 | - | expression tag |
His 534 | - | expression tag |
His 535 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 160768.0 | |
All* | Total formula weight | 160768.0 |