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3FEX

Crystal structure of the CBC-importin alpha complex.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ANuclear cap-binding protein subunit 1polymer79091960.31UniProt (Q09161)
Pfam (PF02854)
Pfam (PF09088)
Pfam (PF09090)
In PDB
Homo sapiens (human)Cap binding protein 80; 80 kDa nuclear cap-binding protein; NCBP 80 kDa subunit; CBP80
2BNuclear cap-binding protein subunit 2polymer15618028.11UniProt (P52298)
Pfam (PF00076)
In PDB
Homo sapiens (human)Cap binding protein 20; 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20, NCBP-interacting protein 1, NIP1, Cell proliferation-inducing gene 55 protein
3CImportin subunit alpha-2polymer46750779.51UniProt (P52292)
Pfam (PF00514)
Pfam (PF16186)
Pfam (PF01749)
In PDB
Homo sapiens (human)Importin alpha 1; Karyopherin subunit alpha-2, SRP1-alpha, RAG cohort protein 1
Sequence modifications
C: 70 - 529 (UniProt: P52292)
PDBExternal DatabaseDetails
Met 69-expression tag
His 530-expression tag
His 531-expression tag
His 532-expression tag
His 533-expression tag
His 534-expression tag
His 535-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight160768.0
All*Total formula weight160768.0
*Water molecules are not included.

217705

건을2024-03-27부터공개중

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