3FA6
Crystal structure of the R132K:Y134F:R111L:L121D:T54V mutant of cellular retinoic acid-binding protein II complexed with C15-aldehyde (a retinal analog) at 1.54 angstrom resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Cellular retinoic acid-binding protein 2 | polymer | 137 | 15493.7 | 2 | UniProt (P29373) Pfam (PF00061) In PDB | Homo sapiens (Human) | Cellular retinoic acid-binding protein II, CRABP-II |
2 | A, B | 1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene | non-polymer | 204.4 | 2 | Chemie (LSR) | |||
3 | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 137 (UniProt: P29373)
PDB | External Database | Details |
---|---|---|
Val 54 | Thr 55 | engineered mutation |
Leu 111 | Arg 112 | engineered mutation |
Asp 121 | Leu 122 | engineered mutation |
Lys 132 | Arg 133 | engineered mutation |
Phe 134 | Tyr 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 30987.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 408.7 | |
All* | Total formula weight | 31396.1 |